Anthracyclinone derivatives and their use in amyloidosis

Details Anthracyclinone derivatives and their use in amyloidosis Anthracyclinone derivatives and their use in amyloidosis

1999-09-14

2000-08-01

Ramsuer, Robert W.

Organic compounds -- part of the class 532-570 series

Organic compounds

Four or more ring nitrogens in the bicyclo ring system

544380, 546195, 546285, 548528, C07D295108

Patent

active

060968885

ABSTRACT:
The present invention provides the new use in the treatment of amyloidosis with the anthracyclinone of formula (A) wherein R1, R2, R3, R4, and R5, are appropriate substituents. Some compounds of formula (A) are novel. Processes for their preparation and pharmaceutical composition containing them are also described.

REFERENCES:
patent: 5744454 (1998-04-01), Suarato et al.
Hartmann et al, Chemical Abstracts, vol. 126, No. 144,048 (1997).
Sumitomo, Chemical Abstracts, vol. 103, No. 141,751 (1985).
Povarov et al. Chemical Abstracts, vol. 91, No. 20926 (1979).

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