Anthracyclines containing branched-chain amino-deoxy sugars

Details Anthracyclines containing branched-chain amino-deoxy sugars Anthracyclines containing branched-chain amino-deoxy sugars

1979-10-05

1981-05-05

Brown, Johnnie R.

Drug, bio-affecting and body treating compositions

Conjugate or complex of monoclonal or polyclonal antibody,...

Conjugated via claimed linking group, bond, chelating agent,...

536 17A, 536 4, 536 53, C07H 1524, A61K 3170

Patent

active

042658853

ABSTRACT:
A new class of antitumor glycoside antibiotics of the formula (IA): ##STR1## wherein R is hydrogen or hydroxy; and X is ##STR2## These compounds are prepared, using novel intermediates, by condensing the appropriate aglycone and branched-chain aminodeoxy sugar to form the .alpha.-glycosidic linkage.

REFERENCES:
patent: 4183919 (1980-01-01), Cassinelli et al.

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