Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Carbohydrate doai
Patent
1996-05-24
1998-01-20
Peselev, Elli
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Carbohydrate doai
536 64, 536 185, 536 186, A61K 3170, C07H 1524
Patent
active
057101353
ABSTRACT:
Anthracycline derivatives are disclosed which are coupled to an enzymatically cleavable N-phenyl-O-glycosyl carbamate spacer group, which derivatives are represented by the formula ##STR1## as well as the acid addition salts thereof. Further the synthesis of these derivatives and their use, alone or in combination with enzymes or antibody enzyme conjugates are disclosed.
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Damen Eric W. P.
de Vos Dick
Haisma Hidde J.
Houba Pieter H. J.
Leenders Ruben G. G.
Peselev Elli
Pharmachemie B.V.
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