Anthracycline glycosides

Details Anthracycline glycosides Anthracycline glycosides

1977-08-09

1978-11-28

Brown, Johnnie R.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

195 80R, 424180, 536 4, C07H 1524

Patent

active

041277147

ABSTRACT:
New antitumor agents designated rhodirubin A and B, which are anthracycline glycosides and inhibit the growth of gram-positive bacteria and mammalian tumors, are produced by fermentation of rhodirubin-producing strains of Streptomyces, e.g. Streptomyces sp. ME 505-HEI (ATCC 31273).

REFERENCES:
patent: 3988315 (1976-10-01), Umezawa et al.
patent: 4039736 (1977-08-01), Nettleton, Jr. et al.
Keller-Schierlein et al., "Antimicrobial Agents and Chemotherapy", 1970, pp. 68-77.

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