Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives
Patent
1979-09-12
1981-05-12
Brown, Johnnie R.
Organic compounds -- part of the class 532-570 series
Organic compounds
Carbohydrates or derivatives
424181, 435 78, A61K 3171, C07H 1524
Patent
active
042673127
ABSTRACT:
New anthracycline derivatives, 1-hydroxy-13-dihydrodaunomycin and N-formyl-1-hydroxy-13-dihydrodaunomycin are produced by microbial transformation of .epsilon.-pyrromycinone and .epsilon.-isorhodomycinone with daunomycin-producing streptomyces and their mutants. The derivatives herein are useful as cancer chemotherapeutic agents.
REFERENCES:
patent: 4039736 (1977-08-01), Nettleton, Jr. et al.
patent: 4146616 (1979-03-01), Penco et al.
Inui Taiji
Oki Toshikazu
Takeuchi Tomio
Umezawa Hamao
Yoshimoto Akihiro
Brown Johnnie R.
Sanraku-Ocean Co., Ltd.
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