Anthracycline-conjugates

Details Anthracycline-conjugates Anthracycline-conjugates

1995-03-27

1998-07-07

Achutamurthy, Ponnathapura

Drug, bio-affecting and body treating compositions

Conjugate or complex of monoclonal or polyclonal antibody,...

4241791, 4241841, 5303917, 5303919, A61K 39395, A61K 3900, C07K 1600, C07K 1700

Patent

active

057764581

ABSTRACT:
The present invention provides anthracycline conjugates with carriers such as monoclonal polyclonal antibodies, proteins or peptides, or other synthetic carriers. These anthracycline conjugates provide pharmaceutical compositions which are useful for treating certain mammalian tumors. The compounds of the present invention have higher potency than anthracyclines, and improved therapeutic efficacy and reduced toxic effects.

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