Anthracycline compounds bound to hydrophilic polypeptides

Details Anthracycline compounds bound to hydrophilic polypeptides Anthracycline compounds bound to hydrophilic polypeptides

1985-05-28

1987-02-10

Schain, Howard E.

Chemistry: natural resins or derivatives; peptides or proteins;

Proteins, i.e., more than 100 amino acid residues

Chemical modification or the reaction product thereof, e.g.,...

424 85, 424 88, 424 89, 424 92, 514 2, 514 21, 530345, 530350, 530402, 530405, 530406, 530410, 530825, 530812, C07K 1702, C07K 1706

Patent

active

046423354

ABSTRACT:
This invention relates to an antitumor composition of anthracycline compounds bonded to hydrophilic polypeptides having a molecular weight between 10,000 and 15,000.

REFERENCES:
patent: 4093607 (1978-06-01), Sela et al.
patent: 4534971 (1985-08-01), Fisher
Cancer Research 35, 1175-1181 (1975), Hurwitz et al.
J. Antibiotics, 36 (9), 1136-1143 (1983), Miyashiro et al.
J. Antibiotics, 37 (1), 20-26 (Jan., 1984), Miyashiro et al.

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