Anthracycline antibiotics produced by Streptosporangium fragilis

Drug – bio-affecting and body treating compositions – Fermentate of unknown chemical structure – Having a known elemental analysis

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424115, 435169, A61K 3500

Patent

active

042935466

ABSTRACT:
A novel anthracycline antibiotic complex, fragilomycin complex, is produced by the cultivation of a fermentation broth containing Streptosporangium fragilis Shearer sp. nov. ATCC 31519 microorganisms in an aqueous nutrient medium under submerged aerobic conditions. The fragilomycin complex and its major bioactive component, fragilomycin A, exhibit antibiotic activity.

REFERENCES:
patent: 3723411 (1973-03-01), Brockmann et al.
The Merck Index, 9th ed., 1976, Merck & Co., Inc., Rahway, N. J. pp. 1062-1063 No. 7982.

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