Anthracycline antibiotics produced by streptosporangium fragile

Details Anthracycline antibiotics produced by streptosporangium fragile Anthracycline antibiotics produced by streptosporangium fragile

1981-08-21

1983-05-24

Wiseman, Thomas G.

Chemistry: molecular biology and microbiology

Micro-organism, per se ; compositions thereof; proces of...

Bacteria or actinomycetales; media therefor

435 64, 435169, 435907, C12N 120, C12P 2700, C12P 106, C12R 162

Patent

active

043851223

ABSTRACT:
A novel anthracycline antibiotic complex, fragilomycin complex, is produced by the cultivation of a fermentation broth containing Streptosporangium fragile Shearer sp. nov. ATCC 31519 microorganisms in an aqueous nutrient medium under submerged aerobic conditions. The fragilomycin complex and its major bioactive component, fragilomycin A, exhibit antibiotic activity.

REFERENCES:
patent: 3723411 (1973-03-01), Brockmann et al.
patent: 4293546 (1981-10-01), Nash et al.
The Merck Index, 9th ed., 1976, Merck and Co. Inc., Rahway, N.J., pp. 1062-1063.

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