Anthracycline antibiotics DCP-1 and 2

Details Anthracycline antibiotics DCP-1 and 2 Anthracycline antibiotics DCP-1 and 2

1987-04-06

1990-01-30

Brown, Johnnie R.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

C07H 1524

Patent

active

048974706

ABSTRACT:
New anthracycline antibiotics of a formula (I) are provided, which are usable as an anticancer agent ##STR1## (where R represents a hydrogen atom or a hydroxyl group). The antibiotics (I) can be produced by incubation of a dye-nonproductive or hardly dye-productive mutant strain which has an ability of converting .alpha.-citromycinone or .beta.-isorhodomycinone into the antibiotics (I), in the presence of .alpha.-citromycinone or .beta.-isorhodomycinone in a pertinent nutrient medium.

REFERENCES:
patent: 4734493 (1988-03-01), Yoshimoto et al.

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