Drug – bio-affecting and body treating compositions – Conjugate or complex of monoclonal or polyclonal antibody,... – Conjugated via claimed linking group – bond – chelating agent,...
Patent
1977-10-03
1980-06-10
Brown, Johnnie R.
Drug, bio-affecting and body treating compositions
Conjugate or complex of monoclonal or polyclonal antibody,...
Conjugated via claimed linking group, bond, chelating agent,...
424180, 536 17R, 536 17A, 536 28, 536 29, 435 78, 435886, A61K 3171, C07H 1524
Patent
active
042073138
ABSTRACT:
New anthracycline glycosides designated MA 144-G1, -G2, -L, -S1, -N1, -U1 and -Y which inhibit the growth of gram-positive bacteria and experimental animal tumors are produced by fermentation of certain species of Streptomyces and by the chemical or enzymatic conversion of certain anthracycline glycosides. New microbiological and chemical processes are also provided for preparation of the anthracycline glycosides MA 144-S2 and -U2 which have been found to be identical with the previously reported anthracyclines, marcellomycin and musettamycin.
REFERENCES:
patent: 3828021 (1974-08-01), Beattie et al.
patent: 3988315 (1976-10-01), Umezawa et al.
patent: 4009328 (1977-02-01), Mallams et al.
patent: 4039736 (1977-08-01), Nettleton, Jr. et al.
patent: 4093797 (1978-06-01), Oda et al.
Nettleton, Jr. et al., "The Jour. of Antibiotics", vol. XXX, No. 6, pp. 525-529, 1977.
Inui Taiji
Oki Toshikazu
Takeuchi Tomio
Umezawa Hamao
Brown Johnnie R.
Morse David M.
Zaidan Hojin Biseibutsu Kagaku Kenkyu Kai
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