Anthracene-spiro-pyrrolindines

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...

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Details

544230, 544372, 548411, 549255, 549331, A61K 31495, C07D40306

Patent

active

054610540

ABSTRACT:
The anthracene-spiro-pyrrolidines according to the invention are prepared by reacting either anthracene-spiro-furans or unsubstituted anthracene-spiropyrrolidines with appropriately substituted amines or by reacting unsubstituted anthracene derivatives with appropriately substituted methylenepyrrolidines. The substances can be used as active agents in medicaments, in particular for the production of immunomodulating medicaments.

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The Journal of Immunology, 1986, vol. 137, pp. 1202-1207, No. 4, Aug. 15, 1986; "Biosynthesis and surface expression of T8 by . . . ", M. L. Blue et al.
Connolly et al., Agents and Actions, 27, pp. 328-331 (1989).
Drug Evaluations by American Medical Association, pp. 401-402, 946 (1993).

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