Anthelmintic fermentation products of microorganisms

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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549264, A61K 31365, C07D49320

Patent

active

047896841

ABSTRACT:
There is disclosed a series of macrolides isolated from the fermentation broth of a microorganism identified as MA-5920. This novel microorganism is formed by the protoplast fusion of strains of Streptomyces avermitilis and Streptomyces hygroscopicus. The structure of the novel compounds isolated from the microorganism is presented based upon analytical studies. The compounds are highly potent antiparasitic, insecticidal, and anthelmintic agents. Compositions for such uses are also disclosed.

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patent: 4289760 (1981-09-01), Mrozik et al.
patent: 4310519 (1982-01-01), Albers-Schonberg et al.
patent: 4378353 (1983-03-01), Goegelman et al.
patent: 4427663 (1984-01-01), Mrozik
patent: 4547520 (1985-10-01), Ide et al.

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