Anthelmintic fermentation products of a microorganism

Details Anthelmintic fermentation products of a microorganism Anthelmintic fermentation products of a microorganism

1986-04-30

1988-08-23

Griffin, Ronald W.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Carbohydrate doai

536 71, 435 76, 435119, A61K 3171, C07H 1708

Patent

active

047661127

ABSTRACT:
There are disclosed macrolides isolated from the fermentation broth, with avermectin Bla, avermectin Blb or 22,23-dihydro avermectin Bla as a substrate, of a known microorganism identified as MA-6181. The structure of the novel compounds isolated from the microorganism are presented based upon analytical studies. The compounds are highly potent antiparasitic, insecticidal, and anthelmintic agents. Compositions for such uses are also disclosed.

REFERENCES:
patent: 4310519 (1982-01-01), Albers-Schonberg et al.
patent: 4378353 (1983-03-01), Goegelman et al.

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