Prosthesis (i.e. – artificial body members) – parts thereof – or ai – Implantable prosthesis – Ligament or tendon
Patent
1995-09-15
1999-05-11
Isabella, David J.
Prosthesis (i.e., artificial body members), parts thereof, or ai
Implantable prosthesis
Ligament or tendon
A61F2/08
Patent
active
059023384
ABSTRACT:
The invention provides an article of manufacture comprising a substantially non-immunogenic ligament or tendon heterografts for implantation into humans. The invention further provides a method for preparing an ligament heterograft by removing at least a portion of an ligament from a non-human animal to provide a heterograft; washing the heterograft in saline and alcohol; subjecting the heterograft to at least one treatment selected from the group consisting of exposure to ultraviolet radiation, immersion in alcohol, ozonation, freeze/thaw cycling, and optionally to chemical crosslinking. In accordance with the invention the heterograft has substantially the same mechanical properties as the native xenogeneic ligament.
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CrossCart, Inc.
Isabella David J.
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