Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...
Patent
1990-04-25
1992-03-03
Lee, Lester L.
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving antigen-antibody binding, specific binding protein...
435 723, 435 72, 435 40, 514 12, 530324, 530325, 930DIG822, 930DIG820, G01N 33567, A61K 3702, C07K 710
Patent
active
050932330
ABSTRACT:
The present invention relates to the use of peptide hormone analogues as inhibitors of their respective naturally occurring peptide hormone. The structure of the peptide hormone analogues is exemplified by parathyroid hormone (PTH), wherein Lys.sup.13 is substituted to increase the biological activity of the PTH analogues. Thus, there are disclosed peptides having the formulae:
REFERENCES:
Horiuchi et al., Science, vol. 238, pp. 1566-1568 (1987).
The Merck Manual, 11th Ed., (1966), pp. 452-453.
Chorev Michael
Nutt Ruth F.
Rosenblatt Michael
Roubini Eliahu
Caruso Charles M.
Lee Lester L.
Merck & Co. , Inc.
Mitri Salvatore C.
Wessendorf T.
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