Antagonists of the vanilloid receptor subtype 1 (VR1) and...

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

Reexamination Certificate

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Details

C514S369000, C514S370000, C514S374000, C514S376000, C514S377000

Reexamination Certificate

active

07902236

ABSTRACT:
The present invention is directed to compounds of formula (I)wherein variables W, X, Y, D, A, n, R1, R2and R9are as defined in the description.

REFERENCES:
patent: 2005/0228031 (2005-10-01), Bilodeau et al.
patent: WO-0230358 (2002-04-01), None
patent: WO-2004072068 (2004-08-01), None
patent: WO-2004110350 (2004-12-01), None
patent: WO-2006044527 (2006-04-01), None
Caterina et al., “Impaired Nociception and Pain Sensation in Mice Lacking the Capsaicin Receptor,” Science, 2000, 306-313, vol. 288.
Davis et al., “Vanilloid receptor-1 is essential for inflammatory thermal hyperalgesia,” (Binary/Image), 2000, 183-187, vol. 405.
Fowler, C. “Intravesical Treatment of Overactive Bladder,” Urology, 2000, 60-64, vol. 55.
International Search Report for application No. PCT/US2006/0018256, Mailed on Oct. 26, 2006, 2 pages.
Nolano et al., “Topical Capsaicin in Humans: Parallel Loss of Epidermal Nerve Fibers and Pain Sensation,” (Binary/Image), 1999, 135-145, vol. 81.
Pircio, A.W. et al., “A New Method for the Evaluation of Analgesic Activity Using Adjuvant-Induced Arthritis in the Rat,” Eur Journal of Pharmacology, 1975, 207-215, vol. 31.
Rasmussen and Bowadt. “Ketene Chemistry 2 A General Procedure for the Synthesis of 2-Alkoxycyclopropane-carboxylic Esters and Acids Starting from Aldehydes and Ketene,” Synthesis, 1989, 114-117.
Wolff “Burger's Medicinal Chemistry”, 1994, 5th Ed, vol. 1, 975-977.

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