Antagonists of organophosphate-induced toxicity

Details Antagonists of organophosphate-induced toxicity Antagonists of organophosphate-induced toxicity

1989-08-10

1991-05-21

Chan, Nicky

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

549370, A61K 31335, C07D31906

Patent

active

050176021

ABSTRACT:
Analogs and congeners of 4,4'-bis-[(1,3-dioxan-2-ylmethyl)aminoacetyl]biphenyl Dimethbromide. The compounds are effective antagonists of paraoxon induced toxicity and antagonized physiological response to certain nerve gas.

REFERENCES:
Cannon et al., J. Med. Chem., 33(2), 577-579 (1990).

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