Antagonists of melanin concentrating hormone effects on the...

Details Antagonists of melanin concentrating hormone effects on the... Antagonists of melanin concentrating hormone effects on the...

2006-05-23

2006-05-23

Saeed, Kamal A. (Department: 1626)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

C514S234500, C514S278000, C514S322000, C514S403000, C514S217090, C540S603000, C544S119000, C546S019000, C546S199000, C548S360100

Reexamination Certificate

active

07049307

ABSTRACT:
The present invention relates to the antagonism of the effects of melanin-concentrating hormone (MCH) through the melanin concentrating hormone receptor which is useful for the prevention or treatment of eating disorders, weight gain, obesity, abnormalities in reproduction and sexual behavior, thyroid hormone secretion, diuresis and water/electrolyte homeostasis, sensory processing, memory, sleeping, arousal, anxiety, depression, seizures, neurodegeneration and psychiatric disorders.

REFERENCES:
patent: 2002/0052373 (2002-05-01), Zorn et al.
patent: 98/30548 (1998-07-01), None
patent: 03/015769 (2003-02-01), None
Zhao et al. (Zhurnal Obshchei Khimii 1959, 29, pp. 1012-1020) CAS Abstract Attached.
Nahon, J-L, “The Melanin-Concentrating Hormone: From the Peptide to the Gene”,Critical Rev in Neurobiology, 8(4):221-262 (1994).

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