Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Reexamination Certificate
2006-02-14
2006-02-14
Dentz, Bernard (Department: 1625)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
C514S302000, C514S440000, C514S443000, C514S465000, C514S466000, C514S469000, C546S114000, C546S115000, C549S015000, C549S057000, C549S436000, C549S462000, C549S466000, C549S468000, C549S470000
Reexamination Certificate
active
06998407
ABSTRACT:
Chemical compounds which are antagonists of Monocyte Chemoattractant Protein-1 (MCP-1) function, pharmaceutical compositions comprising these compounds, methods of treatment employing these compounds and compositions, and processes for preparing these compounds. The compounds are useful in the prevention or treatment of chronic or acute inflammatory or autoimmune diseases, especially those associated with aberrant lymphocyte or monocyte accumulation such as arthritis, asthma, atherosclerosis, diabetic nephropathy, inflammatory bowel disease, Crohn's disease, multiple sclerosis, nephritis, pancreatitis, pulmonary fibrosis, psoriasis, restenosis, and transplant rejection.
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Anuskiewicz Steven E.
Inagaki Hideaki
Ishiwata Yoshiro
Jomori Takahito
Kakigami Takuji
Dentz Bernard
Sanwa Kagaku Kenkyusho Co. Ltd.
Telik, Inc.
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