Antagonists of LHRH

Details Antagonists of LHRH Antagonists of LHRH

1992-09-15

1996-01-02

Warden, Jill

Chemistry: natural resins or derivatives; peptides or proteins;

Peptides of 3 to 100 amino acid residues

8 to 10 amino acid residues in defined sequence

530313, C07K 700, C07K 706, A61K 3800

Patent

active

054809690

ABSTRACT:
LHRH antagonists similar to antide and congeners with higher water solubility have been synthesized by substitutions in positions 1, 5 or 6 with hydrophilic residues. These peptides have antiovulatory activity with minimal histamine releasing effect.

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