Antagonists of gonadotropin releasing hormone

Details Antagonists of gonadotropin releasing hormone Antagonists of gonadotropin releasing hormone

1999-05-14

2000-12-05

Raymond, Richard L.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

5142268, 5142272, 514247, 51425201, 514269, 514307, 514339, 514361, 514392, 514403, 514414, 514333, 544 55, 544 96, 544235, 544284, 544297, 544310, 544316, 544321, 544331, 544353, 544405, 546139, 546153, 546160, 546171, 546172, 546256, 548126, 548131, 548143, 548152, 548156, 548206, 548207, 548212, 548217, 548221, 548233, 548240, 5483001, 5483027, 5483611, 548454, 548455, 548467, A01N 4340, A01N 4338, C07D40100, C07D40500, C07D20902

Patent

active

061567728

ABSTRACT:
There are disclosed compounds of formula (I) ##STR1## and pharmaceutically acceptable salts thereof which are useful as antagonists of GnRH and as such may be useful for the treatment of a variety of sex-hormone related and other conditions in both men and women.

REFERENCES:
patent: 4252803 (1981-02-01), Webb
patent: 4544663 (1985-10-01), Manning et al.
patent: 5030640 (1991-07-01), Fisher et al.
patent: 5245046 (1993-09-01), Youngdale et al.
patent: 5756507 (1998-05-01), Goulet et al.
patent: 5780437 (1998-09-01), Goulet et al.
patent: 5849764 (1998-12-01), Goulet et al.
J. Med. Chem, vol. 32, pp. 2036-2038 (1989), by Clark, et al.

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