Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1996-12-05
1998-05-26
McKane, Joseph
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
514278, 514322, 514323, 514415, 514419, 544373, 546 17, 546199, 546201, 548495, 548496, 548504, A61K 31405, A61K 31495, C07D20910, C07D40306
Patent
active
057565074
ABSTRACT:
There are disclosed compounds of formula (I) ##STR1## and pharmaceutically acceptable salts thereof which are useful as antagonists of GnRH and as such may be useful for the treatment of a variety of sex-hormone related and other conditions in both men and women.
REFERENCES:
patent: 4252803 (1981-02-01), Webb
patent: 4544663 (1985-10-01), Manning et al.
patent: 5030640 (1991-07-01), Fisher et al.
Biswanath De, et al. J. Med. Chem.; 32, pp. 2036-2038 (1989).
Ashton Wallace T.
Bugianesi Robert L.
Chu Lin
Fisher Michael H.
Goulet Mark
Daniel Mark R.
Korsen Elliott
McKane Joseph
Merck & Co. , Inc.
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