Antagonists of gonadotropin releasing hormone

Details Antagonists of gonadotropin releasing hormone Antagonists of gonadotropin releasing hormone

1996-12-05

1998-07-14

Huff, Sheela

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

5142268, 514422, 5142282, 546126, 546131, 546146, 546127, 546128, 546136, 546189, 544242, 544238, 544336, 544 96, 544349, 544255, A61K 3800, A61K 3154, A61K 3140

Patent

active

057804370

ABSTRACT:
There are disclosed compounds of formula (I) ##STR1## and pharmaceutically acceptable salts thereof which are useful as antagonists of GnRH and as such may be useful for the treatment of a variety of sex-hormone related and other conditions in both men and women.

REFERENCES:
patent: 4252803 (1981-02-01), Webb
patent: 4544663 (1985-10-01), Manning et al.
patent: 5030640 (1991-07-01), Fisher et al.
Biswanath De, et al. J. Med. Chem.; 32, pp. 2036-2038 (1989).
R. A. Loy, Current Opinion in Obstetrics and Gynecology, 6, pp. 262-268 (1994).

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