Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Hormones – e.g. – prolactin – thymosin – growth factors – etc.
Reexamination Certificate
2006-02-07
2006-02-07
Carlson, Karen Cochrane (Department: 1653)
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
Hormones, e.g., prolactin, thymosin, growth factors, etc.
Reexamination Certificate
active
06995244
ABSTRACT:
A modified human prolactin molecule wherein the prolactin molecule comprises at least one mutation in a region selected from i) amino acids 41–57, ii) amino acids 94–110, and iii) amino acids 160–173; and wherein the at least one mutation is selected from deletions, replacements, and insertions. The modified prolactins are prolactin antagonists, and can be used in treating cancer, among other conditions.
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Brooks Charles L.
Peterson Francis
Calfee Halter & Griswold
Carlson Karen Cochrane
The Ohio State University
Tsay Marsha
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