Antagonists and agonists of LDCAM and methods of use

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...

Reexamination Certificate

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C530S388240, C530S391100

Reexamination Certificate

active

10898408

ABSTRACT:
The invention pertains to agonists and antagonists of LDCAM and methods of treating disease and infection by administering one or more LDCAM antagonists or agonists. This abstract is provided for the sole purpose of enabling the reader to quickly ascertain the subject matter of the technical disclosure and is not intended to be used to interpret or limit the scope or meaning of the claims.

REFERENCES:
patent: 5686257 (1997-11-01), Kennedy et al.
patent: 6512095 (2003-01-01), Baum
patent: 6642360 (2003-11-01), Filvaroff et al.
patent: 2002/0168712 (2002-11-01), Baum
patent: 2002/0198147 (2002-12-01), Baker et al.
patent: WO97/13844 (1997-04-01), None
patent: WO99/28462 (1999-06-01), None
patent: WO99/57132 (1999-11-01), None
patent: WO00/29435 (2000-05-01), None
patent: WO00/32635 (2000-06-01), None
patent: WO00/32776 (2000-06-01), None
patent: WO01/00237 (2001-01-01), None
patent: WO01/54477 (2001-08-01), None
patent: WO02/26930 (2002-04-01), None
Attwood, T. “The bable of bioinformatics,”Science, 290:47-49, 2000.
Biederer, et al., “SynCAM, a synaptic adhesion molecule that drives synapse assembly,”Science 297:1525-1531, 2002.
Bost, K.L. and Pascual, D.W., “Antibodies against a peptide sequence within the HIV envelope protein crossreacts with human interleukin-2,”Immunol. Invest., 17(6-7):577-586, 1988.
Gomyo, H. et al., “A 2-Mb sequence-ready contig map and a novel immunoglobulin superfamily geneIGSF4in the LOH region of chromosome 11q23.2,”Genomics, 62:139-146, 1999.
Greene, J.L. et al., “Covalent dimerization of CD28/CTLA-4 and oligomerization of CD80/CD86 regulate T cell costimulatory interactions,”J. Biol. Chem., 271(43):26762-26771, 1996.
Kennedy, et al., “A molecular analysis of NKT cells: identification of a class-1 restricted T cell-associated molecule (CRTAM),”J Leuk. Bio. 67:725-734, 2000.
Kuramochi et al., “TSLC1is a tumor-suppressor gene in human non-small-cell lung cancer,”Nat Genet27(4):427-30, 2001.
Linsley, P.S. et al., “Binding stoichiometry of the cytotoxic T lymphocyte-associated molecule-4 (CTLA-4),”J. Biol. Chem., 270(25):15417-15424, 1995.
Masuda et al., “The tumor suppressor protein TSLC1 is involved in cell-cell adhesion,”J Biol Chem. 277(34):31014-31019, 2002.
Metzler et al., “Solution structure of human CTLA-4 and delineation of a CD80/CD86 binding site conserved in CD28,”Nat. Struct. Biol., 4:527-531, 1997.
The Riken Genome Exploration Research Group Phase II Team and the Fantom Consortium; “Functional annotation of a full-length mouse cDNA collection,”Nature 409:685-690, 2001.
Skolnick et al. “From genes to protein structure and function: novel applications of computational approaches in the genomic era,”Trends in Biotech., 18(1):34-39, 2000.
Strausberg, R., NCBI, Accession No. AA493561, Aug. 20, 1997.
Urase K., et al., Expression of RA175 mRNA, a new member of the immunoglobulin superfamily, in developing mouse brain, ,NeuroReport 12(15):3217-3221, 2001.
Wakayama T., et al., “Cloning and Characterization of a Novel Mouse Immunoglobulin Superfamily Gene Expressed in Early Spermatogenic Cells,”Molecular Reproduction and Development 60:158-164, 2001.

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Antagonists and agonists of LDCAM and methods of use does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Antagonists and agonists of LDCAM and methods of use, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Antagonists and agonists of LDCAM and methods of use will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-3735493

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.