Antagonistic analogs of GH-RH inhibiting IGF-I and -II

Details Antagonistic analogs of GH-RH inhibiting IGF-I and -II Antagonistic analogs of GH-RH inhibiting IGF-I and -II

2006-04-11

2006-04-11

Yu, Misook (Department: 1642)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

C530S324000, C530S317000

Reexamination Certificate

active

07026281

ABSTRACT:
There is provided a novel series of synthetic analogs of hGH-RH(1–29)NH2. These analogs inhibit the activity of endogenous hGH-RH, and therefore prevent the release of growth hormone. The stronger inhibitory potencies of the new analogs, as compared to previously described ones, results from replacement of various amino acids.

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