Drug – bio-affecting and body treating compositions – Inorganic active ingredient containing – Aluminum – calcium or magnesium element – or compound containing
Patent
1984-08-08
1990-04-10
Waddell, Frederick E.
Drug, bio-affecting and body treating compositions
Inorganic active ingredient containing
Aluminum, calcium or magnesium element, or compound containing
424692, A61K 3308
Patent
active
049159577
ABSTRACT:
A process for the preparation of an antacid material prepared from magnesium aluminum hydroxide, wherein magnesium hydroxide and/or magnesium oxide is reacted in an atomic ratio of magnesium to aluminum of 1:1 to 3:1 with an aqueous solution of aluminum sulfate until the pH of the reaction mixture is from 4.0 to 8.0, whereafter water-soluble components are removed from the mixture is known manner and this is isolated and, if desired, dried is described as well as a new embodiment of the formula [Mg.sub.5 Al.sub.10 (OH).sub.26 O.sub.5 ](SO.sub.4).sub.2 .multidot.nH.sub.2 O. Also described are pharmaceutical compositions containing such antacid material, in admixture with a conventional pharmaceutical adjuvant, and a method of combating hyperacidity and gastrointestinal diseases, which comprises administering such antacid material.
REFERENCES:
patent: 2923660 (1960-02-01), Hallmann
patent: 3857938 (1974-12-01), Rovati et al.
patent: 4105579 (1978-08-01), Glasscock
Chemical Abstracts, 83 84853e, 1975.
Knecht Adolf
Schneider Michael
Godecke Aktiengesellschaft
Tinney Francis J.
Waddell Frederick E.
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