Drug – bio-affecting and body treating compositions – Inorganic active ingredient containing – Aluminum – calcium or magnesium element – or compound containing
Patent
1996-09-12
1997-07-29
Jordan, Kimberly
Drug, bio-affecting and body treating compositions
Inorganic active ingredient containing
Aluminum, calcium or magnesium element, or compound containing
424686, 424692, 424715, 514666, A61K 3306, A61K 3310, A61K 3308, A61K 3300, A61K 3113
Patent
active
056519974
ABSTRACT:
An antacid composition comprises, as antacid ingredients, a hydrotalcite and dihydroxyaluminium aminoacetate in such a ratio that the former/the latter equals 30/70 to 90/10 (by weight). The composition may further comprises a readily acting or rapid effecting antacid ingredient such as a magnesium hydroxide in an amount of 10 to 50% by weight. The antacid composition is improved in antacid properties and rapid effecting properties, and is useful as a pharmaceutical composition comprising the antacid composition, a carrier, an additive, an additional pharmaceutically active ingredient and so on. The total amount of the antacid ingredients in the pharmaceutical composition may be 10% by weight or more. The pharmaceutical composition may be formed into a fine granule or a granule with utilizing granulation, or into a tablet by compression-molding.
REFERENCES:
patent: 4786505 (1988-11-01), Lovgren et al.
CA102: 172558, Parab et al, 1985.
CA120: 330963, Kim et al., 1993.
"Arzneimittel gegen Hyperazitat (Antazida)", Helwig Arzneimittel, 6th edition, vol. 11, 1988, pp. 38-6 through 38-17, chapter 38.3.
"Organic Chemical Drugs and their Synonyms", M. Negwer, 6th edition, vol. 1, 1987, pp. 9-10.
Rompp Chemie Lexikon, 9th edition, vol. 3, 1990, pp. 1894-1895, paragraph "Hydrotalcit".
Imoto Soichiro
Makino Tadashi
Marunaka Shigeyuki
Jordan Kimberly
Takeda Chemical Industries Ltd.
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