Antacid compositions

Drug – bio-affecting and body treating compositions – Inorganic active ingredient containing – Aluminum – calcium or magnesium element – or compound containing

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Details

424686, 424692, 424715, 514666, A61K 3306, A61K 3310, A61K 3308, A61K 3300, A61K 3113

Patent

active

056519974

ABSTRACT:
An antacid composition comprises, as antacid ingredients, a hydrotalcite and dihydroxyaluminium aminoacetate in such a ratio that the former/the latter equals 30/70 to 90/10 (by weight). The composition may further comprises a readily acting or rapid effecting antacid ingredient such as a magnesium hydroxide in an amount of 10 to 50% by weight. The antacid composition is improved in antacid properties and rapid effecting properties, and is useful as a pharmaceutical composition comprising the antacid composition, a carrier, an additive, an additional pharmaceutically active ingredient and so on. The total amount of the antacid ingredients in the pharmaceutical composition may be 10% by weight or more. The pharmaceutical composition may be formed into a fine granule or a granule with utilizing granulation, or into a tablet by compression-molding.

REFERENCES:
patent: 4786505 (1988-11-01), Lovgren et al.
CA102: 172558, Parab et al, 1985.
CA120: 330963, Kim et al., 1993.
"Arzneimittel gegen Hyperazitat (Antazida)", Helwig Arzneimittel, 6th edition, vol. 11, 1988, pp. 38-6 through 38-17, chapter 38.3.
"Organic Chemical Drugs and their Synonyms", M. Negwer, 6th edition, vol. 1, 1987, pp. 9-10.
Rompp Chemie Lexikon, 9th edition, vol. 3, 1990, pp. 1894-1895, paragraph "Hydrotalcit".

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