Anorexigenic 3-phenyl-tetrahydropyridines

Details Anorexigenic 3-phenyl-tetrahydropyridines Anorexigenic 3-phenyl-tetrahydropyridines

1979-02-02

1980-07-22

Jiles, Henry R.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Bacterium or component thereof or substance produced by said...

546216, 546326, 546346, A61K 3144, C07D21170

Patent

active

042139899

ABSTRACT:
Novel 3-phenyl-tetrahydropyridines of the formula ##STR1## wherein X is selected from the group consisting of hydrogen and chlorine and R is selected from the group consisting of hydrogen, alkyl of 1 to 5 carbon atoms, alkenyl and alkynyl of 3 to 5 carbon atoms and phenyl alkyl of 1 to 3 alkyl carbon atoms with the proviso that X is not hydrogen when R is benzyl and their non-toxic, pharmaceutically acceptable acid addition salts having remarkable anorexigenic properties and inhibition of serontine collection both in vivo and in vitro and their preparation and novel intermediates.

REFERENCES:
patent: 3125488 (1964-03-01), Biel
patent: 3221017 (1965-11-01), Biel
patent: 3284457 (1966-11-01), Beschke et al.

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