Anomer enrichment of alkyl glycosides of amino sugars

Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives

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536 18, 536120, C07H 1504, C07H 506

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active

042503019

ABSTRACT:
Process for enrichment of .beta.-anomers of alkyl glycosides of amino sugars involving two steps. The first step comprises treating an equilibrium mixture of the .alpha.- and .beta.-anomers of the alkyl glycosides with an inorganic base under controlled reaction conditions, e.g., specific solvents, water content of solvent and temperature and time of treatment. These conditions cause the equilibrium to shift in favor of the .beta.-anomer. The second step comprises subjecting the product of the first step to multiple fractionations in specific solvent mixtures to isolate products having increased proportions of the .beta.-anomers of the alkyl glycosides of amino sugars.

REFERENCES:
patent: 4057684 (1977-11-01), Kimura et al.
patent: 4152513 (1979-05-01), Austin et al.

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