Anionic glucofuranose derivatives, methods of making and using t

Details Anionic glucofuranose derivatives, methods of making and using t Anionic glucofuranose derivatives, methods of making and using t

1990-08-03

1992-03-10

Brown, Johnnie R.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

536117, 536118, 536119, 536120, 536121, 536122, C07G 300, C07H 1302, C07H 1504, C07H 2300

Patent

active

050951041

ABSTRACT:
A glucofuranose derivative substituted at the 3,5,6- or 3,6-positions with a radical that provides an anionic charge at physiological pH values is disclosed, as are pharmaceutical compositions, and methods of making and using the same. The compounds are useful in treating inflammation, and particularly conditions that involve neutrophil influx; they are also useful in inhibiting peptic ulcer formation.

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