Anionic furanose derivatives, methods of making and using the sa

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Carbohydrate doai

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536 41, 536117, 536118, 536119, 536120, 536121, 536122, A61K 3170, C07H 1302, C07H 1504, C07H 2300

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active

053589360

ABSTRACT:
A glucofuranose derivative substituted at the 3,5,6- or 3,6-positions with a radical that provides an anionic charge at physiological pH values is disclosed, as are pharmaceutical compositions, and methods of making and using the same. The compounds are useful in treating inflammation, and particularly conditions that involve neutrophil influx; they are also useful in inhibiting gastric ulcer formation.

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