Animal model for preeclampsia

Details Animal model for preeclampsia Animal model for preeclampsia

2006-05-16

2006-05-16

Wilson, Michael (Department: 1632)

Multicellular living organisms and unmodified parts thereof and

Method of using a transgenic nonhuman animal in an in vivo...

Reexamination Certificate

active

07045674

ABSTRACT:
The invention provides an animal model for preeclampsia that allows candidate compounds to be screened for their ability to treat preeclampsia.

REFERENCES:
Takimoto “Hypertension induced in pregnant mice by placental renin and maternal angeiotensinogen,” Science 274(5289): 995-998, 1996.
Makino et al. “Adrenomedullin attenuates the hypertension in hypertensive pregnant rats induced by Ng-nitro-L-arginine methyl ester,” European Journal of Pharmacology 371: 159-167, 1999.
Douglas BH “The rat as a model for preeclampsia.” Perspect Nephrol Hypertens 5:411-419, 1976 (Abstract only).
Crossey et al. “Altered placental development and intrauterine growth restriction in IGF binding protein-1 transgenic mice.” Journal of Clinical Investigation 110(3): 411-418, 2002.
Bohlender et al. “Rats transgenic for human renin and human angiotensinogen as a model for gestational hypertension.” 11(11): 2056-2061, 2000.
Hammer et al. “Spontaneous inflammatory disease in transgenic rats expressing HLA-B27 and human B2m: an animal model of HLA-B27-associated human disorders.” Cell 63: 1099-1112, 1990.
Cameron et al. “Recent advances in transgenic technology.” Molecular Biotechnology 7:253-265, 1997.

Affiliated with

Also associated with

Rating

Animal model for preeclampsia does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Animal model for preeclampsia, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Animal model for preeclampsia will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-3646947