Multicellular living organisms and unmodified parts thereof and – Nonhuman animal
Reexamination Certificate
2011-03-01
2011-03-01
Li, Q. Janice (Department: 1633)
Multicellular living organisms and unmodified parts thereof and
Nonhuman animal
C800S009000
Reexamination Certificate
active
07897833
ABSTRACT:
An animal model for pigment spots in which the formation of pigment spots in human skin is faithfully simulated is provided. An animal model for pigment spots, wherein a black person's skin is grafted onto a non-human animal, is provided.
REFERENCES:
patent: 5719126 (1998-02-01), Nordlund et al.
patent: 7285570 (2007-10-01), Robinson et al.
patent: 2006/0058252 (2006-03-01), Clawson et al.
patent: 2008/0306409 (2008-12-01), Hachiya et al.
Maeda et al. J Dermatol Sci 1997;14:199-206.
Game et al, Wien Klin Wochenschr 2001;113:832-8.
Platt et al. Nat Biotech Mar. 2002;20(3)231-2.
Richardson et al. J Dermol 2006;126:79-84.
Broome Powell. M,, et al., “Hyperpigmentation and Melanocytic Hyperplasia in Transgenic Mice Expressing the Human T24 Ha-rasGene Regulated by a Mouse Tyrosinase Promoter,”Molec. Carcinogenesis12:82-90, Wiley-Liss, Inc. (1995).
Hachiya A:, et al., “An In Vivo Mouse Model of Human Skin Substitute Containing Spontaneously Sorted Melanocytes Demonstrates Physiological Changes after UVB Irradition,”J. Invest. Dermatol. 125:364-372, The Society for Investigative Dermatology, Inc.(2005).
Yoshida, Y., et al., “Functional analysis of keratinocyles in skin color using a human skin substitute model composed of cells derived from different skin pigmentation types,”FASEB J. .21:2829-2839, Federation of American Societies for Experimental Biology (Sep. 2007).
Extended European Search Report for corresponding European Application No. 08007510.4, mailed Sep. 9, 2008, European Patent Office, The Hague.
Hachiya, A., et al,, “The Paracrine Role of Stem Cell Factor/ c-kit Signaling in the Activation of human Melanocytes in Ultraviolet-B-Induced Pigmentation,”J. Invest, Dermatol. 116:578-586, Nature Publishing Group (2001).
Imokawa, G., et al., “Differential Analysis of Experimental Hypermelanosis Induced by UVB, PUVA, and Allergic Contact Dermatitis Using a Brownish Guinea Pig Model,”Arch. Dermatol. Res. 278:352-362, Springer Verlag; (1986).
Kawaguchi, Y., et al., “Kit Melanocytes Seem to Contribute to Melanocyte Proliferation After UV Exposure as Percursor Cells,”J. Invest. Dermatol. 116:920-925, Nature Publishing Group (2001).
Seiberg, M., “Keratinocyte-Melanocyte Interactions During Melanosome Transfer,”Pigment Cell Res. 14:236-242, Munksgaard International Publishers (2001).
Welsh, B.M., et al., “Topical All-transRetinoic Acid Augments Ultraviolet Radiation-Induced Increases in Activated Melanocyte Numbers in Mice,”J. Invest. Dermatol. 112:271-278, Nature Publishing Group (1999).
U.S. Appl. No. 12/073,869, inventors Hachiya, A., et al., filed Mar. 11, 2008 (Not Yet Published).
Dahlen, DD et al, “Soluble Kit receptor blocks stem cell factor bioactivity in vitro,” Letik Res 25(5): 413-21 (May 2001), Elsevier Science Ltd., Oxford, UK.
Hattoyi, H. et. al, “The epidermal stem cell factor is over-expressed in lentigo senilis: implication for the mechanism of hyperpigmentation,” J Invest Dermatol 122(5): 1256-65 (May 2004), Blackwell Publishing Inc., MA.
Kadono, S et al., “The role of the epidermal endothelin cascade in the hyperpigmentation mechanism of lentigo senilis,” J Invest Dermatol 116(4): 571-7 (Apr. 2001), Blackwell Publishing Inc., MA.
Motokawa, T et al., “Messenger RNA levels of melanogenesis-associated genes in lentigo senilis lesions,” J Dermatol Sci 37(2): 120-3 (Feb. 2005), Elsevier Ireland Ltd., Shannon, Ireland.
Hachiya Akira
Sriwiriyanont Penkanok
Kao Corporation
Li Q. Janice
Sterne Kessler Goldstein & Fox P.L.L.C.
LandOfFree
Animal model for pigment spots does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Animal model for pigment spots, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Animal model for pigment spots will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-2669267