Animal model for AIDS

Details Animal model for AIDS Animal model for AIDS

1994-06-03

1997-06-24

Hutzell, Paula K.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

514 16, 530328, 530868, A61K 3808, C07K 706

Patent

active

056417462

ABSTRACT:
A method of inducing symptoms similar to those in AIDS-infected individuals, particularly neurological deficit, wherein peptide T, VIP or gp120 or a derivative or peptide analog thereof is intrathecally administered to non-human mammals.

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Glowa et al., Brain Res 570 (1992) 49-53.
Pert et al., PNAS, 83 (1986) 9254-9258.
Bridge, T.P., et al., Lancet II (1989) 226-227.
Steinman, et al., (abstr.) IXth International Conference on AIDS, Berlin (1993).
Dreyer, E.B., et al., Science, vol. 248, (1990) 364-367.
Gibbons, A., Science, "Is AIDS Dementia Due to Increases in Calcium?" (Apr. 20, 1990) 303.
Dawson, V.L. et al., (abstr.) Society for Neuroscience, vol. 18 (1992) 321.1.

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