Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Bacterium or component thereof or substance produced by said...
Patent
1980-06-23
1981-08-04
Waddell, Frederick E.
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Bacterium or component thereof or substance produced by said...
4242484, 42424854, 42424855, 424263, 424267, A61K 31505, A61K 3154, A61K 3144, A61K 31445
Patent
active
042822289
ABSTRACT:
A process for increasing production in meat-producing, egg-laying or milk-producing animals comprising feeding a compound of the formula: ##STR1## wherein R is a member selected from the group consisting of hydrogen, R.sub.5, ##STR2## wherein R.sub.5 is alkyl of from 1 to 8 carbon atoms, inclusive, including isomeric forms thereof, alkenyl of from 2 to 8 carbon atoms, inclusive, including isomerici forms thereof, cycloalkyl of from 3 to 7 carabon atoms; or lower acyl wherein acyl is up to and including 5 carbon atoms; R.sub.1 is a member selected from the group consisting of R.sub.5 and ##STR3## wherein R.sub.6 is selected from the group consisting of hydrogen, ##STR4## or acyl wherein acyl is up to and including 5 carbon atoms; R.sub.2 is a member selected from the group consisting of hydrogen, R.sub.5, bromo of chloro; R.sub.3 and R.sub.4 are the same or different and are selected from the group consisting of hydrogen, provided that R.sub.3 and R.sub.4 are not both hydrogen, R.sub.5, cycloalkyl of from 3 to 8 carbon atoms, alkyl substituted cycloalkyl of the formula ##STR5## wherein n is an integer of from 2 to 7, inclusive and R.sub.7 is a member selected from the group consisting of hydrogen and alkyl of from 1 to 5 carbon atoms, inclusive, including isomeric forms thereof; alkenyl of from 2 to 8 carbon atoms, inclusive, including isomeric forms thereof, aralkyl wherein Ar is a member selected from the group consisting of phenyl, substituted phenyl wherein 1 or 2 hydrogens are replaced with chlorine, fluorine, bromine, iodine, R.sub.5, --OR.sub.5, or --CF.sub.3 and the substituents can be the same or different, and alkyl is from 1 to 4 carbon atoms, inclusive, including isomeric forms thereof, and R.sub.3 and R.sub.4 taken together with --N< is a heterocyclic moiety of from 4 to 8, inclusive, ring atoms and 1 or 2 hetero atoms selected from the group consisting of nitrogen, oxygen or sulfur or a substituted heterocyclic moiety wherein 0, 1, 2 or 3 of the carbon atoms of the heterocycle are substituted with R.sub.5 in combination with a nutrient animal feed.
REFERENCES:
patent: 3737534 (1973-06-01), Thommen
patent: 3803313 (1974-04-01), Collins
patent: 3870793 (1975-03-01), Collins
patent: 4021562 (1975-12-01), Lawson et al.
DeGeeter Melvin J.
McCall John M.
Killinger John J.
The Upjohn Company
Waddell Frederick E.
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