Animal feed additives

Details Animal feed additives Animal feed additives

1998-10-09

2001-07-24

Witz, Jean C. (Department: 1651)

Drug, bio-affecting and body treating compositions

Enzyme or coenzyme containing

Multienzyme complexes or mixtures of enzymes

C424S094610, C435S200000, C435S209000

Reexamination Certificate

active

06264946

ABSTRACT:

TECHNICAL FIELD
The present invention relates to the combined use in animal feed of one or more xylanolytic enzymes of Type I with one or more xylanolytic enzymes of Type II, as defined herein. It also relates to animal feed and animal feed additives comprising such combination of xylanolytic enzymes.
BACKGROUND ART
The types and amount of plant raw materials which can be used as components in animal feed will often be limited by the ability of the animals to digest them. Feed enhancing enzymes are enzymes, usually of microbial origin, that by improving feed digestibility are able to increase the efficiency of its utilization.
When added to animal feed, feed enhancing enzymes improve the in vivo breakdown of plant cell wall material partly due to a reduction of the intestinal viscosity, whereby a better utilization of the plant nutrients by the animal is achieved. In this way the growth rate and/or feed conversion ratio (i.e. the weight of ingested feed relative to weight gain) of the animal becomes improved.
Xylanolytic enzymes (EC 3.2.1.8) are well known as feed enhancing enzymes. According to one theory, their primary effect is to reduce the viscosity of the feed, whereas another theory focuses on the xylanases increasing the availability of nutrients embedded in the plant cell wall. Thus WO 94/21785 describes xylanases derived from
Aspergillus aculeatus
and their use as animal feed additives, in particular in animal feed compositions containing high amounts of arabinoxylans and glucuronoxylans, e.g. feed containing cereals such as barley, wheat, rye or oats or maize.
WO 95/23514 describes a process for reducing the viscosity of a plant material and for separating plant material into desirable components, which process comprises treating the plant material with a xylanase preparation having a specific activity on water-soluble/water in-soluble pentosans. However, WO 95/23514 does not relate to mixtures of xylanases.
SUMMARY OF THE INVENTION
According to the present invention it has now been found that xylanolytic enzymes can be distinguished by the way they degrade different substrates. Moreover it has surprisingly been found that the combined action of two different types of xylanolytic enzymes is improved as compared to the action of the two separate enzymes, i.e. a synergistic effect occurs.
Therefore, one main object of the invention is the combined use of these two types of xylanolytic enzymes in animal feed. In particular, they are used simultaneously and/or sequentially.
It is another main object of the present invention to provide an animal feed additive which increases energy uptake from animal feed. Accordingly, in one main aspect, the present invention provides an animal feed additive which comprises a mixture of one or more xylanolytic enzymes of Type I with one or more xylanolytic enzymes of Type II, Type I and Type II as defined herein.


REFERENCES:
patent: WO 92/03541 (1992-03-01), None
patent: WO 94/21785 (1994-09-01), None
patent: 9523514 (1995-09-01), None
patent: WO 96/05739 (1996-02-01), None
patent: WO 96/23062 (1996-08-01), None
He et al. (1994) Enzyme Microb Technol 16:696-702.
He et al., (1993) Enzyme Microb. Technol. 15:13-18.

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