Aniline derivatives, their manufacture and use as...

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

Reexamination Certificate

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Details

C548S146000, C548S202000, C548S203000, C548S204000

Reexamination Certificate

active

07345067

ABSTRACT:
This invention relates to compounds of the formulawhereinX is N and Y is S or O; orX is S or O and Y is N;R1is hydrogen or C1-7-alkyl;R2and R3independently from each other are selected from the group consisting of hydrogen, C1-7-alkyl and C1-7-alkoxy;R4, R5, R6, and R7independently from each other are selected from the group consisting of hydrogen, C1-7-alkyl, C3-7-cycloalkyl, halogen, C1-7-alkoxy, C1-7-alkyl-C1-7-alkoxy-C1-7-alkyl, C2-7-alkenyl, C2-7-alkinyl, fluoro-C1-7-alkyl and cyano;R8is selected from the group consisting of hydrogen, C1-7-alkyl, C3-7-cycloalkyl and fluoro-C1-7-alkyl;R9is selected from the group consisting of hydrogen, C1-7-alkyl, C2-7-alkinyl, C3-7-cycloalkyl and fluoro-C1-7-alkyl;R10is selected from the group consisting of hydrogen, C1-7-alkyl, C2-7-alkinyl, C3-7-cycloalkyl and fluoro-C1-7-alkyl;R11is aryl or heteroaryl;N is 0, 1 or 2;and all enantiomers and pharmaceutically acceptable salts and/or esters thereof and their use as PPAR activators.

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patent: WO 03 072102 (2003-09-01), None

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