Anilide derivative, production and use thereof

Details Anilide derivative, production and use thereof Anilide derivative, production and use thereof

1998-12-17

2000-12-26

Powers, Fiona T.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

514311, 514314, 514319, 514320, 514357, 514422, 514431, 514432, 514450, 514451, 514617, 540593, 544145, 544147, 544331, 546173, 546202, 546205, 546333, 546196, 548517, 549 9, 549 28, 549424, 549355, 564 16, 564180, A61K 31165, A61K 31351, A61K 314453, A61K 3155, C07C23362, C07D21106, C07D23316, C07D30904, C07D40510

Patent

active

06166006&

ABSTRACT:
This invention is to provide a compound of the formula: ##STR1## wherein R.sup.1 is an optionally substituted 5- to 6-membered ring: C is a divalent group of the formula: ##STR2## wherein the ring A is an optionally substituted 5- to 6-membered aromatic ring, X is an optionally substituted C, N or O atom, and the ring B is an optionally substituted 5- to 7-membered ring; Z is a chemical bond or a divalent group; R.sup.2 is (1) an optionally substituted amino group in which a nitrogen atom may form a quaternary ammonium, etc., or a salt thereof, which is useful for antagonizing MCP-1 receptor.

REFERENCES:
Derwent Abstract of JP 07025756-A, Jan. 27, 1995.
Derwent Abstract of JP 07025757-A, Jan. 27, 1995.

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