Anhydrous form of dasatinib and process for preparation thereof

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

Reexamination Certificate

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C544S328000, C544S369000, C548S205000

Reexamination Certificate

active

07973045

ABSTRACT:
The invention provides anhydrous forms of dasatinib, methods for their preparation, and pharmaceutical compositions thereof.

REFERENCES:
patent: 4728653 (1988-03-01), Campbell et al.
patent: 5250534 (1993-10-01), Bell et al.
patent: 6333198 (2001-12-01), Edmeades et al.
patent: 6596746 (2003-07-01), Das et al.
patent: 6976694 (2005-12-01), Das et al.
patent: 7091223 (2006-08-01), Das et al.
patent: 7125875 (2006-10-01), Das et al.
patent: 7153856 (2006-12-01), Barrish et al.
patent: 7189854 (2007-03-01), Das et al.
patent: 7408069 (2008-08-01), Schaefer et al.
patent: 7491725 (2009-02-01), Lajeunesse et al.
patent: 2005/0176965 (2005-08-01), Chen et al.
patent: 2005/0215795 (2005-09-01), Chen et al.
patent: 2006/0004067 (2006-01-01), Chen et al.
patent: 2006/0211705 (2006-09-01), Arora et al.
patent: 2007/0037978 (2007-02-01), Schaefer et al.
patent: 2007/0219370 (2007-09-01), Sun et al.
patent: 2009/0149650 (2009-06-01), Chen et al.
patent: 463756 (1992-01-01), None
patent: WO 00/62778 (2000-10-01), None
patent: WO 2004/085388 (2004-10-01), None
patent: WO 2005/076990 (2005-08-01), None
patent: WO 2005/077945 (2005-08-01), None
patent: WO 2007/019210 (2007-02-01), None
patent: WO 2007/035874 (2007-03-01), None
Caira, “Crystalline Polymorphism of Organic Compounds”, Topics in Current Chemistry, Springer, Berlin, DE, Jan. 1, 1998, vol. 198, p. 163-208.
Das et al., “2-aminothiazole as a Novel Kinase Inhibitor Template. Structure-Activity Relationship Studies Toward the Discovery of N-(2-Chloro-6-methylphenyl)-2[[6-[4-(2-hydroxyethyl)-1-piperazinyl)]2-methyl-4-pyrimidinyl]amino)]-1,3-thiazole-5-carboxamide (Dasatinib, BMS-354825) as a Potent pan-Src Kinase Inh”, Journal of Medicinal Chemistry, Nov. 2006, vol. 49, No. 23, p. 6819-6832.
Strobel et al., Chemical Instrumentation: A Systematic Approach, 3rd ed., Wiley & Sons: New York, p. 391-393, 879,894, 922, 924, 925, 953 (1989).
Snyder et al., Introduction to Modern Liquid Chromatography, 2nd ed., John Wiley & Sons, New York, p. 571-572, 549, 552 (1979).
International Search Report and Written Opinion of ISA, dated Oct. 15, 2009, from International Patent Application PCT/IB2008/003862.
Zhao, et al., “A new facile synthesis of 2-aminothiazole-5-carboxylates,” Tetrahedron Letters, 42: 2102-02 (2001).

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Anhydrous form of dasatinib and process for preparation thereof does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Anhydrous form of dasatinib and process for preparation thereof, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Anhydrous form of dasatinib and process for preparation thereof will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-2633693

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.