Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Blood proteins or globulins – e.g. – proteoglycans – platelet...
Patent
1988-09-21
1989-06-27
Moskowitz, Margaret
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
Blood proteins or globulins, e.g., proteoglycans, platelet...
530389, 530387, 530405, 530409, 530807, 424 858, 436823, C07K 308, C07K 1706, A61K 39395
Patent
active
048431478
ABSTRACT:
An improvement in a method to conjugate a protein which must resist denaturation with a variable component using a carbodiimide condensing agent utilizes a polar aprotic solvent as the medium for condensation. This improvement results in shorter reaction times and improved coupling efficiency.
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Atassi et al., Bioch. Biophys. Acta., 670, 300-302, (1981).
Levy Julia G.
Liu Daniel
Kushan Jeff P.
Moskowitz Margaret
University of British Columbia
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