Anhydrous composition, stable to oxidation, based on anthralin o

Details Anhydrous composition, stable to oxidation, based on anthralin o Anhydrous composition, stable to oxidation, based on anthralin o

1982-10-22

1985-01-22

Schenkman, Leonard

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

C-o-group doai

424365, 514863, A61K 3105

Patent

active

044952031

ABSTRACT:
Anhydrous composition, stable to oxidation, of anthralin or a derivative thereof.
This composition contains anthralin or a derivative thereof in a carrier composed of (i) at least one fatty acid alkyl ester, the fatty acid having 12 to 18 carbon atoms and the alkyl radical having 2 or 3 carbon atoms, and (ii) at least one thickener taken from the group made up of silicas having particle sizes less than 30 m.mu. and polyethylene powders having densities between 0.9 and 0.96 (g/cm.sup.3).
This composition is used in the treatment of skin diseases, particularly psoriasis.

REFERENCES:
patent: 4203969 (1980-05-01), Yarrow et al.
patent: 4287214 (1981-09-01), Van Scott et al.
patent: 4299826 (1981-11-01), Luedders
patent: 4316902 (1982-02-01), Yu et al.
patent: 4367224 (1983-01-01), Van Scott et al.
Remington's Pharmaceutical Sciences, 16th Ed., 1980, p. 356.
Chemical Abstracts 76:144782y (1972).
Cosmetics, Science & Technology (Balsam et al.), 2nd Ed., vol. 1, pp. 194-195, (1972).

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