Drug – bio-affecting and body treating compositions – Anti-perspirants or perspiration deodorants
Reexamination Certificate
2000-01-27
2001-08-14
Dodson, Shelley A. (Department: 1616)
Drug, bio-affecting and body treating compositions
Anti-perspirants or perspiration deodorants
C424S066000, C424S067000, C424S068000, C424S400000
Reexamination Certificate
active
06274127
ABSTRACT:
TECHNICAL FIELD
The present invention relates to antiperspirant compositions and corresponding methods of application, wherein the compositions comprise a new antiperspirant active in the form of water-reactive monomers.
BACKGROUND OF THE INVENTION
Many topical antiperspirant products are commercially available in a variety of formulations and product forms. These products typically contain a solid and/or liquid carrier in combination with an antiperspirant active such as an aluminum and/or zirconium salt. These aluminum and zirconium salts are used in almost every commercial antiperspirant product and have been used in this manner for decades.
Antiperspirant actives help to reduce or eliminate perspiration on the underarm or other areas of the skin. It is believed that these antiperspirant actives work by dissolving in sweat after application, diffusing as a dissolved material into the sweat ducts, and then precipitating in the sweat ducts to form a plug that then inhibits the flow of perspiration. It is believed that aluminum and zirconium salts work in this manner.
Today, commercially viable antiperspirant actives are limited mostly to the zirconium and aluminum salts. Other alternative actives have been investigated for antiperspirant efficacy over the years with very little practical success. Examples of such alternative actives include anticholinergics, antiadrenergics, aldehydes, and metabolic inhibitors such as oubain.
Still other alternative antiperspirant actives include water-insoluble, occlusive, film-forming polymers when applied topically to the skin. Examples of such antiperspirant polymers are described in U.S. Pat. No. 5,508,024, issued to Frank Tranner on Apr. 16, 1996. The application of these water-insoluble, polymeric films, however, often results in poor wash-off and application cosmetics. It has also been found that the application of these films does not always improve antiperspirant efficacy as compared to the application of commercially available antiperspirant products containing conventional zirconium and aluminum salts.
It has now been found that water-reactive monomers can be used as alternative antiperspirant actives to those actives currently available or otherwise known in the art. It has also been found that these water-reactive monomers can provide improved antiperspirant efficacy and/or cosmetics, especially when compared to the application of the antiperspirant polymers described hereinabove. These water-reactive monomers are formulated in an anhydrous base and applied topically to the underarm or other area of the skin. The topically applied monomers react with sweat and polymerize at the opening of the sweat ducts to form small polymeric plugs at the surfaces of the ducts, thus inhibiting or preventing the flow of perspiration from the affected ducts.
The topical application of water-reactive monomers has not previously been described in the context of antiperspirant products. These water-reactive monomers are, however, well known in the various arts for formulating topical adhesives and occlusive barrier films. Application of these formulations has been described primarily in the context of surgical wound adhesives, topically applied occlusive films and other similar applications.
It is therefore an object of the present invention to provide alternative antiperspirant compositions and antiperspirant actives to those which are currently available or otherwise known in the art. It is a further object of the present invention to provide such alternative compositions and antiperspirant actives through the use and application of water-reactive monomers contained by or within a suitable anhydrous carrier, and further to provide such alternative compositions and actives with improved antiperspirant efficacy and/or cosmetics.
SUMMARY OF THE INVENTION
The present invention is directed to antiperspirant compositions comprising novel antiperspirant active in the form of water-reactive monomers. These compositions preferably form discontinuous polymer-containing films on the skin, topically positioned over sweat ducts in the skin, wherein the polymer-containing films are derived from water-reactive monomers that react with sweat at the opening of the sweat ducts, to thereby polymerize and form the discontinuous polymer-containing films. The polymer-containing films over the sweat ducts act as plugs within the ducts to help prevent or inhibit the flow of perspiration from the affected sweat ducts. The present invention is also directed to methods for inhibiting or preventing perspiration by topically applying to the underarm or other appropriate area of skin a water-reactive monomer composition as described herein, which composition preferably comprises a water-reactive monomer, an anhydrous carrier, and a suitable polymerization inhibitor or other effective polymerization inhibition means.
It has been found that these topical antiperspirant compositions and applied methods of application provide alternative antiperspirant formulations and methods from those commercially available or otherwise known, without reliance upon traditional antiperspirant actives such as zirconium and aluminum salts. It has also been found that these compositions and applied methods provide improved antiperspirant efficacy and/or cosmetics as compared to many other more traditional antiperspirant products.
DETAILED DESCRIPTION OF THE INVENTION
The antiperspirant compositions of the present invention comprise water-reactive monomers, an anhydrous carrier, and preferably a suitable polymerization inhibitor or other effective polymerization inhibition means. These compositions are applied topically to the underarm or other appropriate area of the skin as a non-adhesive composition to inhibit or prevent perspiration.
The term “anhydrous” as used herein, unless otherwise specified, refers to those materials or compositions that are substantially free of added water. As it pertains to the compositions of the present invention, this means that the compositions are sufficiently free of added water such that the water-reactive monomers remain substantially unreacted or unpolymerized, e.g., less than about 50% reacted, prior to application. In this context, the term “anhydrous” can also mean that the composition contains water but that the water is isolated or otherwise prevented from reacting with the water-reactive monomer in the composition. The term “anhydrous” as used herein generally means that the material or composition preferably contains less than 1%, preferably less than 0.5%, most preferably zero percent, by weight of free or added water.
The term “non-adhesive” as used herein, unless otherwise specified, refers generally to the compositions of the present invention and the corresponding skin feel characteristics of those compositions when topically applied to the skin, wherein the compositions adhere to the applied surface of the skin but do not result in cosmetically noticeable adhesion of adjacent skin surfaces or clothing to the applied surface of the skin. These non-adhesive compositions are also preferably non-sticky after application.
The term “antiperspirant efficacy” as used herein, unless otherwise specified, refers to any incremental sweat reduction resulting from an antiperspirant composition as a result of the addition of the water-reactive monomer described herein. Sweat reduction is determined by the hot room procedure described in the Federal Register Volume 43, number 196 paragraph 350.43.
The term “water-reactive monomer” as used herein, unless otherwise specified, refers to those monomers or oligomers that react with water or sweat to polymerize under ambient conditions, or which otherwise react and polymerize during or after application to the underarm or other area of the skin. The term “water-reactive monomer” as used herein, unless otherwise specified, includes monomers and oligomers.
The term “ambient conditions” as used herein, refers to surrounding conditions at about one atmosphere of pressure (1 atm), at about 50% relative humidity, unless oth
Gardlik John Michael
Raleigh Patricia Sue
Schraer Robert Michael
Dodson Shelley A.
The Procter & Gamble & Company
Winter William J.
LandOfFree
Anhydrous antiperspirant compositions containing... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Anhydrous antiperspirant compositions containing..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Anhydrous antiperspirant compositions containing... will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-2502189