Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives
Patent
1977-09-16
1979-12-04
Brown, Johnnie R.
Organic compounds -- part of the class 532-570 series
Organic compounds
Carbohydrates or derivatives
424180, 536 1, 536119, 536120, C07H 310
Patent
active
041773446
ABSTRACT:
The invention relates to novel 1,6-anhydro-.beta.-D-hexopyranose derivatives of the formula I ##STR1## in which R.sub.2 is hydrogen, methyl or aromatic acyl, R.sub.3 and R.sub.4 are alkyl, alkenyl or aralkyl and one of the radicals R.sub.3 and R.sub.4 is also an aroyl radical and R.sub.4 can also be hydrogen, with the proviso that the radicals R.sub.3 and R.sub.4 together contain at least 3 carbon atoms and, if R.sub.4 is the benzyl radical, the radical R.sub.3 contains at least 2 carbon atoms, and, if one of the radicals R.sub.3 and R.sub.4 is an aroyl radical, R.sub.2 is hydrogen.
These compounds especially the 1,6-anhydro-3,4-di-O-benzyl-.beta.-D-glucopyranose or the 1,6-anhydro-.beta.-D-glucopyranose, can be used as fibrinolytic agents and thrombolytic agents.
REFERENCES:
patent: 3305542 (1967-02-01), Carlberg et al.
patent: 3414560 (1968-12-01), Carlberg et al.
patent: 3914212 (1975-10-01), Baschang et al.
"Advances in Carbohydrate Chemistry", vol. 23, 1968, pp. 437-442.
"Advances in Carbohydrate Chemistry", vol. 26, 1971, pp. 55-60.
Baschang Gerhard
Rossi Alberto
Sele Alex
Stanek Jaroslav
Brown Johnnie R.
Ciba-Geigy Corporation
Maitner John J.
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