Anhydro-sugars

Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives

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424180, 536 1, 536119, 536120, C07H 310

Patent

active

041773446

ABSTRACT:
The invention relates to novel 1,6-anhydro-.beta.-D-hexopyranose derivatives of the formula I ##STR1## in which R.sub.2 is hydrogen, methyl or aromatic acyl, R.sub.3 and R.sub.4 are alkyl, alkenyl or aralkyl and one of the radicals R.sub.3 and R.sub.4 is also an aroyl radical and R.sub.4 can also be hydrogen, with the proviso that the radicals R.sub.3 and R.sub.4 together contain at least 3 carbon atoms and, if R.sub.4 is the benzyl radical, the radical R.sub.3 contains at least 2 carbon atoms, and, if one of the radicals R.sub.3 and R.sub.4 is an aroyl radical, R.sub.2 is hydrogen.
These compounds especially the 1,6-anhydro-3,4-di-O-benzyl-.beta.-D-glucopyranose or the 1,6-anhydro-.beta.-D-glucopyranose, can be used as fibrinolytic agents and thrombolytic agents.

REFERENCES:
patent: 3305542 (1967-02-01), Carlberg et al.
patent: 3414560 (1968-12-01), Carlberg et al.
patent: 3914212 (1975-10-01), Baschang et al.
"Advances in Carbohydrate Chemistry", vol. 23, 1968, pp. 437-442.
"Advances in Carbohydrate Chemistry", vol. 26, 1971, pp. 55-60.

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