Angiotensin II receptor blocking 2,3,6 substituted quinazolinone

Details Angiotensin II receptor blocking 2,3,6 substituted quinazolinone Angiotensin II receptor blocking 2,3,6 substituted quinazolinone

1992-01-14

1994-03-01

Shah, Mukund J.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

544284, 544287, A61K 31505, C07D40310, C07D23991

Patent

active

052907805

ABSTRACT:
Novel quinazolinone compounds of the formula: ##STR1## wherein R.sup.5, R.sup.6, R.sup.7, R.sup.8, R and X are defined in the specification, which have angiotensin II (AII) antagonizing activity, intermediates useful in the preparation of the compounds, methods of producing and using the compounds to alleviate angiotensin induced hypertension and treat congestive heart failure in mammals.

REFERENCES:
patent: 4797403 (1989-01-01), Lowe, III
patent: 4992550 (1991-02-01), Hughes
patent: 5240928 (1993-09-01), Allen et al.
Chiu et al., European Journal of Pharmacology 157(1988) 13-21.

Affiliated with

Also associated with

Rating

Angiotensin II receptor blocking 2,3,6 substituted quinazolinone does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Angiotensin II receptor blocking 2,3,6 substituted quinazolinone, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Angiotensin II receptor blocking 2,3,6 substituted quinazolinone will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-577267