Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Reexamination Certificate
2007-12-11
2010-11-16
Saeed, Kamal A (Department: 1626)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
C548S250000
Reexamination Certificate
active
07834042
ABSTRACT:
A compound having the structure (Formula I), wherein Y is —Y1—Y2—Y3—Y4—Y5—; Y1is C(O) or C(R1R2); Y2is O, C(O), P(O)(OH) or CH2, provided that when Y1is C(O), Y2is not C(O); R1is selected from the group consisting of hydrogen and C1-4alkyl; R2is selected from the pup consisting of hydrogen, C1-4alkyl, and —OC(O)C1-4alkyl; Y3is O, C(O) or CH2, provided that when Y2is C(O), then Y3is not C(O), and further provided that when Y2is O, then Y3is not O; Y4is O or CH2or is absent, provided that when Y3is O, then Y4is not O; Y5 is —(CH2)1-2—(X)0-1—(CH2)0-1— or is absent; X is —O— or —CR3R4—; and R3and R4are independently selected from the group consisting of hydrogen and C1-C4alkyl; or a pharmaceutically acceptable salt thereof, which is useful for treating hypertension.
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Ali Amjad
Lo Michael Man-chu
Nargund Ravi P.
Sebhat Iyassu K.
Berman Paul J.
Covington & Burling LLP
Merck Sharp & Dohme Corp.
Saeed Kamal A
Shterengarts Samantha L
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