Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Phosphorus containing other than solely as part of an...
Reexamination Certificate
2011-05-24
2011-05-24
Loewe, Sun Jae Y (Department: 1626)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Phosphorus containing other than solely as part of an...
C548S250000
Reexamination Certificate
active
07947664
ABSTRACT:
A compound having the structurewherein R is an angiotensin receptor antagonist active group,Y is selected from the group consisting ofand2) —C(R1H)OC(O)X((CR12R13)—(CHR10)m—(CH2)n—Zp—(CH2)q—(CHR11)r—(CR16R17))—R5;Z is —O— or —(CR14R15)—;m, n, p, q, and r are independently selected from the group consisting of 0 and 1;X is —O— or —(CR18R19)—;R1is selected from the group consisting of hydrogen, C1-4alkyl, aryl and C1-4alkylaryl;R5is —O—N═N(O)—NR3R4;or a pharmaceutically acceptable salt or hydrate thereof, which is useful for treating hypertension.
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patent: WO2009/099853 (2009-08-01), None
AngiotensinIIReceptorAntagonist, http://en.wikipedia.org/wiki/Angiotensin—II—receptor—antagonist, 2010.
US International Search Report; completed Feb. 24, 2009; Performed by Authorized Officer Lee W. Young.
Ali Amjad
Franklin Christopher
Lo Michael Man-chu
Whitehead Brent R.
Daniel Mark R.
Loewe Sun Jae Y
Merck Sharp & Dohme Corp.
Parr Richard S.
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