Angiotensin II receptor antagonistic 1,2,4-triazin-5-one derivat

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...

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Details

544182, 544319, 544179, 514269, 514183, C07D253065, A61K 3153

Patent

active

060719133

ABSTRACT:
Disclosed are novel 1,2,4-triazin-5-one biphenyl derivatives having structural formula (I) useful as non-peptide antagonists of angiotensin II receptor: ##STR1## where R.sub.1 represents alkyl, cycloalkyl, or substituted or unsubstituted aryl;

REFERENCES:
patent: 4880804 (1989-11-01), Carini et al.
patent: 5225408 (1993-07-01), Weller, III
patent: 5534534 (1996-07-01), Makino et al.

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