Angiotensin II antagonists

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...

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514 81, 514211, 540490, 540487, 540502, A61K 3155, C07D48722

Patent

active

050648250

ABSTRACT:
Novel substituted imidazo-fused 7-member ring heterocycles of the formulae (I) and (Ia), which are useful as angiotensin II antagonists, are disclosed. ##STR1##

REFERENCES:
patent: 4207324 (1980-06-01), Matsumura et al.
patent: 4340598 (1982-07-01), Furukawa et al.
patent: 4576958 (1986-03-01), Wexler
patent: 4582847 (1986-04-01), Furukawa et al.
P. G. Wong et al., J. Pharmcol. Exp. Ther., "Nonpeptide Angiotension II Receptor Antagonists", 247(1), pp. 1-(1988).
P. K. Bridson et al., Journal of Heterocyclic Chemistry, "Cyclic Homologs of Xanthins", 25(4), pp. 1179-1182 (1988).

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